Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAD18RAD18 E3 ubiquitin protein ligase. (479 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen.
   
 0.988
HLTF
Helicase like transcription factor.
   
 0.978
SHPRH
SNF2 histone linker PHD RING helicase.
    
 0.971
ENSSDAP00000015770
annotation not available
    
 
 0.968
SLF1
SMC5-SMC6 complex localization factor 1.
   
 
 0.967
UBE2A
Ubiquitin conjugating enzyme E2 A.
    
 0.953
UBE2B
Ubiquitin conjugating enzyme E2 B.
    
 0.953
ENSSDAP00000022901
annotation not available
   
 
 0.951
ENSSDAP00000022914
annotation not available
   
 
 0.951
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
    
 0.948
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
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