Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROCK2Rho associated coiled-coil containing protein kinase 2. (1145 aa)    
Predicted Functional Partners:
ROCK1
Rho associated coiled-coil containing protein kinase 1.
   
 0.999
PPP1R12A
Protein phosphatase 1 regulatory subunit 12A.
   
 0.994
ENSSDAP00000002653
annotation not available
   
 0.989
MYL9
Myosin light chain 9.
    
 0.982
LIMK1
LIM domain kinase 1.
    
 0.981
LIMK2
LIM domain kinase 2.
    
 0.980
MYL2
Myosin light chain 2.
    
 0.978
GAB1
GRB2 associated binding protein 1.
   
  0.973
MYL10
Myosin light chain 10.
    
 0.968
CTNNB1
Catenin beta 1.
    
 0.963
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
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