close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKK1Dickkopf WNT signaling pathway inhibitor 1. (267 aa)    
Predicted Functional Partners:
LRP6
LDL receptor related protein 6.
    
 0.998
LRP5
LDL receptor related protein 5.
    
 0.992
KREMEN1
Kringle containing transmembrane protein 1.
    
 0.982
KREMEN2
Kringle containing transmembrane protein 2.
    
 0.969
LRP4
LDL receptor related protein 4.
    
 0.933
ENSSDAP00000003232
annotation not available
    
 0.933
LRP1
LDL receptor related protein 1.
    
 0.933
LRP2
LDL receptor related protein 2.
    
 0.933
ENSSDAP00000020935
annotation not available
    
 0.933
WNT6
Wnt family member 6.
    
 0.918
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.