Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM74Transmembrane protein 74. (307 aa)    
Predicted Functional Partners:
LRCH4
Leucine rich repeats and calponin homology domain containing 4.
      
 0.628
CDADC1
Cytidine and dCMP deaminase domain containing 1.
      
 0.614
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.608
PRRG4
Proline rich and Gla domain 4.
      
 0.599
PAK1IP1
PAK1 interacting protein 1.
      
 0.590
ATG16L2
Autophagy related 16 like 2.
    
 
 0.590
SNAP47
Synaptosome associated protein 47.
      
 0.574
ARSA
Arylsulfatase A.
      
 0.559
WDR20
WD repeat domain 20.
      
 0.522
ATG16L1
Autophagy related 16 like 1.
    
 
 0.511
Your Current Organism:
Spermophilus dauricus
NCBI taxonomy Id: 99837
Other names: Citellus dauricus, Daurian ground squirrel, S. dauricus
Server load: low (22%) [HD]