Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HMGB2Uncharacterized protein. (210 aa)    
Predicted Functional Partners:
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.613
G1SL50_RABIT
Uncharacterized protein.
   
  0.596
HMGB1
High-mobility group box 1 (Predicted).
   
  0.596
G1U2M7_RABIT
HMG box domain-containing protein.
   
  0.596
ENSOCUP00000023657
annotation not available
   
  0.596
ENSOCUP00000033999
annotation not available
   
  0.596
ENSOCUP00000049279
Uncharacterized protein.
   
  0.596
ENSOCUP00000049648
Uncharacterized protein.
   
  0.596
ENSOCUP00000043114
Uncharacterized protein.
   
  0.588
AGER
Advanced glycosylation end-product specific receptor.
    
 0.573
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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