Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (521 aa)    
Predicted Functional Partners:
C1S
Complement C1s; Belongs to the peptidase S1 family.
   
 0.997
C1R
Complement C1r; Belongs to the peptidase S1 family.
   
 0.996
G1SSI4_RABIT
GLOBIN domain-containing protein; Belongs to the globin family.
   
 
  0.994
MASP1
Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
   
 0.964
C1QB
Complement C1q B chain.
   
 0.963
C1QA
Complement C1q A chain.
   
 0.949
F12
Coagulation factor XII.
   
 0.934
SERPINF2
SERPIN domain-containing protein; Belongs to the serpin family.
  
 
0.931
SERPINC1
Serpin family C member 1; Belongs to the serpin family.
  
0.930
MBL2
Mannose binding lectin 2.
     
 0.902
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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