F8 protein (Oryctolagus cuniculus) - STRING interaction network

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS13	F8	ENSOCUP00000049297	ENSOCUP00000049694	ACR domain-containing protein.	Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family.	0.844
ADAMTS13	MUC5B	ENSOCUP00000049297	ENSOCUP00000037515	ACR domain-containing protein.	Uncharacterized protein.	0.802
ADAMTS13	VWF	ENSOCUP00000049297	ENSOCUP00000023792	ACR domain-containing protein.	Von Willebrand factor.	0.998
F10	F5	ENSOCUP00000025032	ENSOCUP00000025128	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	Coagulation factor V.	0.973
F10	F7	ENSOCUP00000025032	ENSOCUP00000042756	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).	0.970
F10	F8	ENSOCUP00000025032	ENSOCUP00000049694	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family.	0.954
F10	F9	ENSOCUP00000025032	ENSOCUP00000004537	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	Coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.	0.502
F10	PROC	ENSOCUP00000025032	ENSOCUP00000041616	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.	0.647
F10	VWF	ENSOCUP00000025032	ENSOCUP00000023792	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	Von Willebrand factor.	0.496
F5	F10	ENSOCUP00000025128	ENSOCUP00000025032	Coagulation factor V.	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	0.973
F5	F7	ENSOCUP00000025128	ENSOCUP00000042756	Coagulation factor V.	Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).	0.830
F5	F8	ENSOCUP00000025128	ENSOCUP00000049694	Coagulation factor V.	Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family.	0.810
F5	F9	ENSOCUP00000025128	ENSOCUP00000004537	Coagulation factor V.	Coagulation factor IX; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.	0.852
F5	LMAN1	ENSOCUP00000025128	ENSOCUP00000024695	Coagulation factor V.	Lectin, mannose binding 1.	0.865
F5	MUC5B	ENSOCUP00000025128	ENSOCUP00000037515	Coagulation factor V.	Uncharacterized protein.	0.650
F5	PROC	ENSOCUP00000025128	ENSOCUP00000041616	Coagulation factor V.	Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.	0.964
F5	PROS1	ENSOCUP00000025128	ENSOCUP00000018723	Coagulation factor V.	Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.	0.955
F5	VWF	ENSOCUP00000025128	ENSOCUP00000023792	Coagulation factor V.	Von Willebrand factor.	0.735
F7	F10	ENSOCUP00000042756	ENSOCUP00000025032	Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).	Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.	0.970
F7	F5	ENSOCUP00000042756	ENSOCUP00000025128	Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).	Coagulation factor V.	0.830