STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WWP1E3 ubiquitin-protein ligase. (877 aa)    
Predicted Functional Partners:
SMAD7
Mothers against decapentaplegic homolog.
    
 0.929
SPART
Spartin.
   
 
 0.901
ENSOCUP00000044498
Ribosomal_L40e domain-containing protein.
    
 0.875
KLF5
Uncharacterized protein.
   
 0.845
EGFR
Receptor protein-tyrosine kinase.
    
 0.844
LOC100345190
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.822
RNF11
Ring finger protein 11.
    
 0.816
ITCH
E3 ubiquitin-protein ligase.
  
0.808
NDFIP2
Nedd4 family interacting protein 2.
    
 
 0.803
NDFIP1
Nedd4 family interacting protein 1.
    
 
 0.799
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.