Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)    
Predicted Functional Partners:
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
   
 0.999
LAMTOR4
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4.
   
 0.998
SLC38A9
Solute carrier family 38 member 9.
    
 0.997
LAMTOR1
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.
   
 0.996
LAMTOR5
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5.
   
 0.995
RRAGC
Ras related GTP binding C.
   
 0.995
RRAGD
Ras related GTP binding D.
    
 0.990
RRAGA
Ras related GTP binding A.
   
 0.983
ENSOCUP00000041843
Uncharacterized protein.
   
 0.981
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]
   
 0.975
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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