SERINC4 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SERINC4

Serine incorporator 4. (427 aa)

Predicted Functional Partners:

SERINC3

0.690

SERINC1

0.679

ELL3

0.674

SERF2

0.640

MFAP1

0.562

LOC100340649

0.560

RYR3

0.557

TRIM5

0.554

CPA5

0.547

SERINC2

0.546

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPA5	SERINC1	ENSOCUP00000006052	ENSOCUP00000013567	Carboxypeptidase A5.	Serine incorporator 1.	0.495
CPA5	SERINC4	ENSOCUP00000006052	ENSOCUP00000001009	Carboxypeptidase A5.	Serine incorporator 4.	0.547
ELL3	SERINC4	ENSOCUP00000001007	ENSOCUP00000001009	Uncharacterized protein.	Serine incorporator 4.	0.674
LOC100340649	SERINC4	ENSOCUP00000035226	ENSOCUP00000001009	CMP/dCMP-type deaminase domain-containing protein.	Serine incorporator 4.	0.560
LOC100340649	TRIM5	ENSOCUP00000035226	ENSOCUP00000043699	CMP/dCMP-type deaminase domain-containing protein.	Uncharacterized protein.	0.579
MFAP1	SERF2	ENSOCUP00000009224	ENSOCUP00000034412	Microfibrillar-associated protein 1 (Predicted).	Small EDRK-rich factor 2.	0.616
MFAP1	SERINC4	ENSOCUP00000009224	ENSOCUP00000001009	Microfibrillar-associated protein 1 (Predicted).	Serine incorporator 4.	0.562
RYR3	SERINC4	ENSOCUP00000045001	ENSOCUP00000001009	Ryanodine receptor 3; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Plays a role in cellular calcium signaling. Contributes to cellular calcium ion homeostasis. Isoform 2 lacks a predicted transmembrane segment and does not form functional calcium channels by itself; however, it can form tetramers [...]	Serine incorporator 4.	0.557
SERF2	MFAP1	ENSOCUP00000034412	ENSOCUP00000009224	Small EDRK-rich factor 2.	Microfibrillar-associated protein 1 (Predicted).	0.616
SERF2	SERINC4	ENSOCUP00000034412	ENSOCUP00000001009	Small EDRK-rich factor 2.	Serine incorporator 4.	0.640
SERINC1	CPA5	ENSOCUP00000013567	ENSOCUP00000006052	Serine incorporator 1.	Carboxypeptidase A5.	0.495
SERINC1	SERINC4	ENSOCUP00000013567	ENSOCUP00000001009	Serine incorporator 1.	Serine incorporator 4.	0.679
SERINC2	SERINC4	ENSOCUP00000013662	ENSOCUP00000001009	Serine incorporator 2.	Serine incorporator 4.	0.546
SERINC3	SERINC4	ENSOCUP00000003686	ENSOCUP00000001009	Serine incorporator 3.	Serine incorporator 4.	0.690
SERINC3	TRIM5	ENSOCUP00000003686	ENSOCUP00000043699	Serine incorporator 3.	Uncharacterized protein.	0.496
SERINC4	CPA5	ENSOCUP00000001009	ENSOCUP00000006052	Serine incorporator 4.	Carboxypeptidase A5.	0.547
SERINC4	ELL3	ENSOCUP00000001009	ENSOCUP00000001007	Serine incorporator 4.	Uncharacterized protein.	0.674
SERINC4	LOC100340649	ENSOCUP00000001009	ENSOCUP00000035226	Serine incorporator 4.	CMP/dCMP-type deaminase domain-containing protein.	0.560
SERINC4	MFAP1	ENSOCUP00000001009	ENSOCUP00000009224	Serine incorporator 4.	Microfibrillar-associated protein 1 (Predicted).	0.562
SERINC4	RYR3	ENSOCUP00000001009	ENSOCUP00000045001	Serine incorporator 4.	Ryanodine receptor 3; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm in muscle and thereby plays a role in triggering muscle contraction. May regulate Ca(2+) release by other calcium channels. Calcium channel that mediates Ca(2+)-induced Ca(2+) release from the endoplasmic reticulum in non-muscle cells. Plays a role in cellular calcium signaling. Contributes to cellular calcium ion homeostasis. Isoform 2 lacks a predicted transmembrane segment and does not form functional calcium channels by itself; however, it can form tetramers [...]	0.557