Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
FRKFyn related Src family tyrosine kinase. (389 aa)    
Predicted Functional Partners:
MIPOL1
Mirror-image polydactyly 1.
   
  
 0.974
MST1R
Macrophage stimulating 1 receptor.
   
 0.926
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.886
EGFR
Receptor protein-tyrosine kinase.
    
  0.814
KIAA1328
KIAA1328.
   
    0.804
LOC100346323
Uncharacterized protein.
    
 0.775
G1U4G6_RABIT
Uncharacterized protein.
    
  0.697
ENSOCUP00000047396
Uncharacterized protein.
    
  0.697
SH2D1A
SH2 domain containing 1A.
   
 0.696
PTK2-2
FERM_N_2 domain-containing protein.
 
 
 0.650
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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