Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKR1D1 | CYP11B2 | ENSOCUP00000014594 | ENSOCUP00000012891 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.922 |
| AKR1D1 | CYP17A1 | ENSOCUP00000014594 | ENSOCUP00000015281 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.922 |
| AKR1D1 | CYP19A1 | ENSOCUP00000014594 | ENSOCUP00000010591 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | 0.913 |
| AKR1D1 | CYP21A2 | ENSOCUP00000014594 | ENSOCUP00000006096 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.918 |
| AKR1D1 | HSD17B2 | ENSOCUP00000014594 | ENSOCUP00000014316 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.913 |
| AKR1D1 | HSD17B3 | ENSOCUP00000014594 | ENSOCUP00000007373 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.912 |
| AKR1D1 | LOC100346986 | ENSOCUP00000014594 | ENSOCUP00000034335 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. | 0.971 |
| AKR1D1 | SRD5A1 | ENSOCUP00000014594 | ENSOCUP00000014623 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. | 0.966 |
| AKR1D1 | SRD5A2 | ENSOCUP00000014594 | ENSOCUP00000001070 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. | 0.966 |
| AKR1D1 | SRD5A3 | ENSOCUP00000014594 | ENSOCUP00000015962 | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | S5A_REDUCTASE domain-containing protein. | 0.909 |
| CYP11B2 | AKR1D1 | ENSOCUP00000012891 | ENSOCUP00000014594 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Aldo-keto reductase family 1 member D1; Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta- hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3- one); Belongs to the aldo/keto reductase family. | 0.922 |
| CYP11B2 | CYP17A1 | ENSOCUP00000012891 | ENSOCUP00000015281 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. | 0.959 |
| CYP11B2 | CYP19A1 | ENSOCUP00000012891 | ENSOCUP00000010591 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. | 0.942 |
| CYP11B2 | CYP21A2 | ENSOCUP00000012891 | ENSOCUP00000006096 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. | 0.961 |
| CYP11B2 | HSD17B2 | ENSOCUP00000012891 | ENSOCUP00000014316 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.920 |
| CYP11B2 | HSD17B3 | ENSOCUP00000012891 | ENSOCUP00000007373 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Hydroxysteroid 17-beta dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.927 |
| CYP11B2 | LOC100346986 | ENSOCUP00000012891 | ENSOCUP00000034335 | Uncharacterized protein; Belongs to the cytochrome P450 family. | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. | 0.956 |
| CYP11B2 | SRD5A1 | ENSOCUP00000012891 | ENSOCUP00000014623 | Uncharacterized protein; Belongs to the cytochrome P450 family. | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. | 0.925 |
| CYP11B2 | SRD5A2 | ENSOCUP00000012891 | ENSOCUP00000001070 | Uncharacterized protein; Belongs to the cytochrome P450 family. | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. | 0.924 |
| CYP11B2 | SRD5A3 | ENSOCUP00000012891 | ENSOCUP00000015962 | Uncharacterized protein; Belongs to the cytochrome P450 family. | S5A_REDUCTASE domain-containing protein. | 0.917 |
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