Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ESRP2Epithelial splicing regulatory protein 2. (719 aa)    
Predicted Functional Partners:
ESRP1
Epithelial splicing regulatory protein 1.
   
 
  0.792
ENAH
ENAH actin regulator.
   
  
 0.789
RBPMS
RNA binding protein, mRNA processing factor.
    
 
 0.708
RBM47
RNA binding motif protein 47.
   
 
 0.707
CTNND1
Catenin delta 1.
   
  
 0.701
RBM4
RNA-binding protein 4; RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation [...]
    
 0.674
RBFOX2
RNA binding fox-1 homolog 2.
     
 0.668
GRHL1
Grainyhead like transcription factor 1.
   
  
 0.656
FGFR2
Fibroblast growth factor receptor.
      
 0.630
GRHL2
Grainyhead like transcription factor 2.
   
  
 0.583
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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