Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LMBR1Limb development membrane protein 1; Belongs to the LIMR family. (490 aa)    
Predicted Functional Partners:
RNF32
Ring finger protein 32.
    
 
 0.696
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
    
 0.692
LETMD1
LETM1 domain containing 1.
    
 
 0.689
CFAP65
Cilia and flagella associated protein 65.
      
 0.675
NOM1
Nucleolar protein with MIF4G domain 1.
      
 0.619
EPRS1
Glutamyl-prolyl-tRNA synthetase.
    
 
 0.552
BCO2
Beta-carotene oxygenase 2.
      
 0.477
ZP2
Processed zona pellucida sperm-binding protein 2; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. Belongs to the ZP domain family. ZPA subfamily.
      
 0.472
WNT8B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.470
SLC35F3
Solute carrier family 35 member F3.
      
 0.468
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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