EDNRA protein (Oryctolagus cuniculus) - STRING interaction network

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Score

EDNRA

Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)

Predicted Functional Partners:

EDN1

0.998

EDN3

0.981

EDN2

0.969

AGT

0.905

GNA13

0.888

GNA12

0.879

KNG1

0.876

GNAI2

0.869

BDKRB2

0.862

EDNRB

0.858

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	BDKRB2	ENSOCUP00000000417	ENSOCUP00000012746	Angiotensinogen; Belongs to the serpin family.	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	0.931
AGT	EDN1	ENSOCUP00000000417	ENSOCUP00000011526	Angiotensinogen; Belongs to the serpin family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.779
AGT	EDN3	ENSOCUP00000000417	ENSOCUP00000046269	Angiotensinogen; Belongs to the serpin family.	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	0.414
AGT	EDNRA	ENSOCUP00000000417	ENSOCUP00000001082	Angiotensinogen; Belongs to the serpin family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.905
AGT	EDNRB	ENSOCUP00000000417	ENSOCUP00000015272	Angiotensinogen; Belongs to the serpin family.	Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.	0.899
AGT	KNG1	ENSOCUP00000000417	ENSOCUP00000033073	Angiotensinogen; Belongs to the serpin family.	Kininogen 1.	0.825
BDKRB2	AGT	ENSOCUP00000012746	ENSOCUP00000000417	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	Angiotensinogen; Belongs to the serpin family.	0.931
BDKRB2	EDN1	ENSOCUP00000012746	ENSOCUP00000011526	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.888
BDKRB2	EDNRA	ENSOCUP00000012746	ENSOCUP00000001082	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.862
BDKRB2	EDNRB	ENSOCUP00000012746	ENSOCUP00000015272	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.	0.857
BDKRB2	GNAI2	ENSOCUP00000012746	ENSOCUP00000019624	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	G protein subunit alpha i2.	0.861
BDKRB2	KNG1	ENSOCUP00000012746	ENSOCUP00000033073	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	Kininogen 1.	0.995
EDN1	AGT	ENSOCUP00000011526	ENSOCUP00000000417	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Angiotensinogen; Belongs to the serpin family.	0.779
EDN1	BDKRB2	ENSOCUP00000011526	ENSOCUP00000012746	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.	0.888
EDN1	EDN2	ENSOCUP00000011526	ENSOCUP00000001041	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	0.896
EDN1	EDN3	ENSOCUP00000011526	ENSOCUP00000046269	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	0.885
EDN1	EDNRA	ENSOCUP00000011526	ENSOCUP00000001082	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.998
EDN1	EDNRB	ENSOCUP00000011526	ENSOCUP00000015272	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.	0.999
EDN1	KNG1	ENSOCUP00000011526	ENSOCUP00000033073	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Kininogen 1.	0.547
EDN2	EDN1	ENSOCUP00000001041	ENSOCUP00000011526	Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.896