Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LTBRLymphotoxin beta receptor. (414 aa)    
Predicted Functional Partners:
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.994
LTB
Lymphotoxin beta; Belongs to the tumor necrosis factor family.
   
 0.992
TNFSF14
TNF superfamily member 14.
    
 0.992
LTA
Lymphotoxin-alpha; Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
   
 0.985
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.981
TRAF1
TNF receptor-associated factor.
    
 0.971
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
    
 0.807
TNFSF11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
    
 0.794
TNFRSF1A
TNF receptor superfamily member 1A.
   
 
0.792
TNLG7A
Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.
    
 0.762
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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