Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ESRP1Epithelial splicing regulatory protein 1. (680 aa)    
Predicted Functional Partners:
RBPMS
RNA binding protein, mRNA processing factor.
    
 
 0.838
ENAH
ENAH actin regulator.
      
 0.816
GRHL2
Grainyhead like transcription factor 2.
   
  
 0.795
ESRP2
Epithelial splicing regulatory protein 2.
   
 
  0.792
QKI
QKI, KH domain containing RNA binding.
    
 0.758
CTNND1
Catenin delta 1.
   
  
 0.733
RBFOX2
RNA binding fox-1 homolog 2.
     
 0.716
RAB25
Ras-related protein Rab-25; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). ECO:0000250|UniProtKB:P57735, ECO:0000250|UniProtKB:Q9WTL2,; Belongs to the small GTPase superfamily. Rab family.
   
  
 0.683
FGFR2
Fibroblast growth factor receptor.
      
 0.682
GRHL1
Grainyhead like transcription factor 1.
   
  
 0.669
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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