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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SREK1Splicing regulatory glutamic acid and lysine rich protein 1. (618 aa)    
Predicted Functional Partners:
SRSF3
Serine and arginine rich splicing factor 3.
   
 0.809
PNISR
PNN interacting serine and arginine rich protein.
   
 
 0.753
SRSF5
Serine and arginine rich splicing factor 5.
   
 0.705
PNN
Pinin, desmosome associated protein.
   
 
 0.641
SRSF1
Uncharacterized protein.
   
 0.622
SRSF7
CCHC-type domain-containing protein.
   
 0.621
SRSF6
Serine/arginine-rich-splicing factor 6.
   
 0.606
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.581
SRRM1
PWI domain-containing protein.
   
 0.571
U3KPG1_RABIT
Uncharacterized protein.
   
 0.570
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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