| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC100338723 | SLC3A2 | ENSOCUP00000016820 | ENSOCUP00000001148 | Uncharacterized protein. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...] | 0.884 |
| LOC100338723 | SLC7A9 | ENSOCUP00000016820 | ENSOCUP00000028774 | Uncharacterized protein. | B(0,+)-type amino acid transporter 1; Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule; Belongs to the amino acid-polyamine-organocation (APC) superfamily. | 0.848 |
| SLC1A2 | SLC3A2 | ENSOCUP00000000621 | ENSOCUP00000001148 | Amino acid transporter. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...] | 0.871 |
| SLC1A2 | SLC7A10 | ENSOCUP00000000621 | ENSOCUP00000008143 | Amino acid transporter. | Solute carrier family 7 member 10. | 0.662 |
| SLC1A2 | SLC7A11 | ENSOCUP00000000621 | ENSOCUP00000001420 | Amino acid transporter. | Solute carrier family 7 member 11. | 0.500 |
| SLC1A2 | SLC7A6 | ENSOCUP00000000621 | ENSOCUP00000007362 | Amino acid transporter. | Uncharacterized protein. | 0.609 |
| SLC1A2 | SLC7A7 | ENSOCUP00000000621 | ENSOCUP00000048478 | Amino acid transporter. | Solute carrier family 7 member 7. | 0.611 |
| SLC1A2 | SLC7A8 | ENSOCUP00000000621 | ENSOCUP00000019754 | Amino acid transporter. | Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administe [...] | 0.805 |
| SLC1A2 | SLC7A9 | ENSOCUP00000000621 | ENSOCUP00000028774 | Amino acid transporter. | B(0,+)-type amino acid transporter 1; Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule; Belongs to the amino acid-polyamine-organocation (APC) superfamily. | 0.690 |
| SLC1A2 | TFRC | ENSOCUP00000000621 | ENSOCUP00000014641 | Amino acid transporter. | Transferrin receptor. | 0.489 |
| SLC1A5 | SLC3A2 | ENSOCUP00000007892 | ENSOCUP00000001148 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...] | 0.893 |
| SLC1A5 | SLC7A10 | ENSOCUP00000007892 | ENSOCUP00000008143 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | Solute carrier family 7 member 10. | 0.632 |
| SLC1A5 | SLC7A11 | ENSOCUP00000007892 | ENSOCUP00000001420 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | Solute carrier family 7 member 11. | 0.506 |
| SLC1A5 | SLC7A6 | ENSOCUP00000007892 | ENSOCUP00000007362 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | Uncharacterized protein. | 0.599 |
| SLC1A5 | SLC7A7 | ENSOCUP00000007892 | ENSOCUP00000048478 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | Solute carrier family 7 member 7. | 0.569 |
| SLC1A5 | SLC7A8 | ENSOCUP00000007892 | ENSOCUP00000019754 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | Large neutral amino acids transporter small subunit 2; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administe [...] | 0.819 |
| SLC1A5 | SLC7A9 | ENSOCUP00000007892 | ENSOCUP00000028774 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | B(0,+)-type amino acid transporter 1; Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule; Belongs to the amino acid-polyamine-organocation (APC) superfamily. | 0.532 |
| SLC1A5 | TFRC | ENSOCUP00000007892 | ENSOCUP00000014641 | Neutral amino acid transporter B(0); Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. | Transferrin receptor. | 0.635 |
| SLC3A2 | LOC100338723 | ENSOCUP00000001148 | ENSOCUP00000016820 | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...] | Uncharacterized protein. | 0.884 |
| SLC3A2 | SLC1A2 | ENSOCUP00000001148 | ENSOCUP00000000621 | 4F2 cell-surface antigen heavy chain; Component of several heterodimeric amino acid transporter complexes. The precise substrate specificity depends on the other subunit in the heterodimer (By similarity). The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, leucine, histidine, methionine and tryptophan. The complexes with SLC7A6 and SLC7A7 mediate uptake of dibasic amino acids. The complexes function as amino acid exchangers. Required for targeting of SLC7A5 and [...] | Amino acid transporter. | 0.871 |
