STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTSGCathepsin G. (250 aa)    
Predicted Functional Partners:
MPO
Myeloperoxidase.
   
 0.999
MMP9
Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).
   
 0.949
CTRL
Chymotrypsin like; Belongs to the peptidase S1 family.
  
 0.842
LTF
Lactotransferrin; Belongs to the transferrin family.
   
 0.813
BPI
Bactericidal permeability-increasing protein; The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
   
 
 0.778
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.761
SERPINA1
Alpha-1-antiproteinase F; Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin; Belongs to the serpin family.
    
 0.734
CTSS
Cathepsin S; Belongs to the peptidase C1 family.
     
 0.711
CASP1
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.703
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
     
 0.694
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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