Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IKZF3IKAROS family zinc finger 3. (509 aa)    
Predicted Functional Partners:
CRBN
Cereblon.
    
 
 0.989
IKZF1
IKAROS family zinc finger 1.
   
 
 0.952
IKZF4
IKAROS family zinc finger 4.
   
   0.936
IKZF5
Uncharacterized protein.
   
 
0.831
CHD4
Uncharacterized protein.
    
 0.794
HDAC2
Histone deacetylase 2.
    
 0.771
IKZF2
IKAROS family zinc finger 2.
   
   0.768
DDB1
Damage specific DNA binding protein 1.
    
 0.738
PAX5
Paired box 5.
   
 0.706
ZPBP2
Zona pellucida binding protein 2.
   
 
 0.704
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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