HNRNPD protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HNRNPD

Heterogeneous nuclear ribonucleoprotein D. (286 aa)

Predicted Functional Partners:

HNRNPU

0.913

HNRNPL

0.845

HNRNPK

0.840

FUS

0.827

TNPO1

0.823

EIF4G1

0.817

HNRNPH1

0.803

HNRNPA3

0.791

HNRNPF

0.775

ENSOCUP00000047449

0.774

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4G1	HNRNPD	ENSOCUP00000032992	ENSOCUP00000001170	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	Heterogeneous nuclear ribonucleoprotein D.	0.817
EIF4G1	HNRNPK	ENSOCUP00000032992	ENSOCUP00000008932	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	0.593
ENSOCUP00000047449	FUS	ENSOCUP00000047449	ENSOCUP00000020899	Uncharacterized protein.	FUS RNA binding protein.	0.436
ENSOCUP00000047449	HNRNPD	ENSOCUP00000047449	ENSOCUP00000001170	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein D.	0.774
ENSOCUP00000047449	HNRNPK	ENSOCUP00000047449	ENSOCUP00000008932	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	0.532
ENSOCUP00000047449	HNRNPL	ENSOCUP00000047449	ENSOCUP00000023948	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein L; Belongs to the enoyl-CoA hydratase/isomerase family.	0.502
ENSOCUP00000047449	HNRNPU	ENSOCUP00000047449	ENSOCUP00000044849	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein U.	0.400
FUS	ENSOCUP00000047449	ENSOCUP00000020899	ENSOCUP00000047449	FUS RNA binding protein.	Uncharacterized protein.	0.436
FUS	HNRNPA3	ENSOCUP00000020899	ENSOCUP00000002378	FUS RNA binding protein.	Uncharacterized protein.	0.565
FUS	HNRNPD	ENSOCUP00000020899	ENSOCUP00000001170	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein D.	0.827
FUS	HNRNPF	ENSOCUP00000020899	ENSOCUP00000027381	FUS RNA binding protein.	Uncharacterized protein.	0.582
FUS	HNRNPH1	ENSOCUP00000020899	ENSOCUP00000036364	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein H1.	0.578
FUS	HNRNPK	ENSOCUP00000020899	ENSOCUP00000008932	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]	0.781
FUS	HNRNPL	ENSOCUP00000020899	ENSOCUP00000023948	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein L; Belongs to the enoyl-CoA hydratase/isomerase family.	0.835
FUS	HNRNPU	ENSOCUP00000020899	ENSOCUP00000044849	FUS RNA binding protein.	Heterogeneous nuclear ribonucleoprotein U.	0.752
FUS	TNPO1	ENSOCUP00000020899	ENSOCUP00000011467	FUS RNA binding protein.	Transportin 1.	0.954
HNRNPA3	FUS	ENSOCUP00000002378	ENSOCUP00000020899	Uncharacterized protein.	FUS RNA binding protein.	0.565
HNRNPA3	HNRNPD	ENSOCUP00000002378	ENSOCUP00000001170	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein D.	0.791
HNRNPA3	HNRNPF	ENSOCUP00000002378	ENSOCUP00000027381	Uncharacterized protein.	Uncharacterized protein.	0.751
HNRNPA3	HNRNPH1	ENSOCUP00000002378	ENSOCUP00000036364	Uncharacterized protein.	Heterogeneous nuclear ribonucleoprotein H1.	0.714