STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)    
Predicted Functional Partners:
TLN1
Talin 1.
   
 0.999
TLN2
Talin 2.
   
 0.999
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
   
 0.999
ITGAE
Integrin subunit alpha E; Belongs to the integrin alpha chain family.
   
 0.983
FN1
Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
    
 0.981
MADCAM1
Uncharacterized protein.
    
 0.977
ILK
Integrin linked kinase.
    
 0.968
ITGA5
Integrin subunit alpha 5; Belongs to the integrin alpha chain family.
   
 0.953
FLNA
Uncharacterized protein.
    
 0.948
PTK2-2
FERM_N_2 domain-containing protein.
   
 0.945
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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