Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHSA1 | CHORDC1 | ENSOCUP00000001230 | ENSOCUP00000012157 | Activator of HSP90 ATPase activity 1. | Uncharacterized protein. | 0.743 |
| AHSA1 | ENSOCUP00000043890 | ENSOCUP00000001230 | ENSOCUP00000043890 | Activator of HSP90 ATPase activity 1. | PPIase cyclophilin-type domain-containing protein. | 0.692 |
| AHSA1 | FKBP4 | ENSOCUP00000001230 | ENSOCUP00000048194 | Activator of HSP90 ATPase activity 1. | Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May [...] | 0.686 |
| AHSA1 | HSP90AB1 | ENSOCUP00000001230 | ENSOCUP00000012976 | Activator of HSP90 ATPase activity 1. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.750 |
| AHSA1 | HSP90B1 | ENSOCUP00000001230 | ENSOCUP00000014008 | Activator of HSP90 ATPase activity 1. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. | 0.724 |
| AHSA1 | NKTR | ENSOCUP00000001230 | ENSOCUP00000027236 | Activator of HSP90 ATPase activity 1. | Natural killer cell triggering receptor. | 0.692 |
| AHSA1 | PPID | ENSOCUP00000001230 | ENSOCUP00000005706 | Activator of HSP90 ATPase activity 1. | Peptidylprolyl isomerase D. | 0.710 |
| AHSA1 | PPIG | ENSOCUP00000001230 | ENSOCUP00000009538 | Activator of HSP90 ATPase activity 1. | Peptidylprolyl isomerase G. | 0.695 |
| AHSA1 | PTGES3 | ENSOCUP00000001230 | ENSOCUP00000029851 | Activator of HSP90 ATPase activity 1. | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.744 |
| AHSA1 | STIP1 | ENSOCUP00000001230 | ENSOCUP00000029749 | Activator of HSP90 ATPase activity 1. | Stress induced phosphoprotein 1. | 0.844 |
| CHORDC1 | AHSA1 | ENSOCUP00000012157 | ENSOCUP00000001230 | Uncharacterized protein. | Activator of HSP90 ATPase activity 1. | 0.743 |
| CHORDC1 | HSP90AB1 | ENSOCUP00000012157 | ENSOCUP00000012976 | Uncharacterized protein. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.485 |
| CHORDC1 | HSP90B1 | ENSOCUP00000012157 | ENSOCUP00000014008 | Uncharacterized protein. | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. | 0.606 |
| ENSOCUP00000043890 | AHSA1 | ENSOCUP00000043890 | ENSOCUP00000001230 | PPIase cyclophilin-type domain-containing protein. | Activator of HSP90 ATPase activity 1. | 0.692 |
| ENSOCUP00000043890 | HSP90AB1 | ENSOCUP00000043890 | ENSOCUP00000012976 | PPIase cyclophilin-type domain-containing protein. | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.667 |
| ENSOCUP00000043890 | PTGES3 | ENSOCUP00000043890 | ENSOCUP00000029851 | PPIase cyclophilin-type domain-containing protein. | Prostaglandin E synthase 3; Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway. | 0.867 |
| ENSOCUP00000043890 | STIP1 | ENSOCUP00000043890 | ENSOCUP00000029749 | PPIase cyclophilin-type domain-containing protein. | Stress induced phosphoprotein 1. | 0.771 |
| FKBP4 | AHSA1 | ENSOCUP00000048194 | ENSOCUP00000001230 | Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May [...] | Activator of HSP90 ATPase activity 1. | 0.686 |
| FKBP4 | HSP90AB1 | ENSOCUP00000048194 | ENSOCUP00000012976 | Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May [...] | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] | 0.727 |
| FKBP4 | HSP90B1 | ENSOCUP00000048194 | ENSOCUP00000014008 | Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May [...] | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. | 0.495 |
page 1 of 4