STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNA12G protein subunit alpha 12. (457 aa)    
Predicted Functional Partners:
ARHGEF12
Rho guanine nucleotide exchange factor 12.
    
 0.991
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.990
GNA13
G protein subunit alpha 13.
  
 
0.984
S1PR2
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.981
LPAR1
Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.971
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.969
RHOA
Ras homolog family member A.
    
 0.965
ADRA1A
Alpha-1A adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity); Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily.
    
 0.961
S1PR3
Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.960
S1PR5
Sphingosine-1-phosphate receptor 5; Belongs to the G-protein coupled receptor 1 family.
    
 0.960
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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