MEP1A protein (Oryctolagus cuniculus) - STRING interaction network

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Score

MEP1A

Meprin A subunit. (749 aa)

Predicted Functional Partners:

MEP1B

0.975

PRCP

0.947

ACE2

0.920

XPNPEP2

0.903

MME

0.875

CLTRN

0.845

TMEM174

0.829

XPNPEP1

0.793

PHEX

0.744

GCG

0.734

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	GCG	ENSOCUP00000015275	ENSOCUP00000019727	Angiotensin-converting enzyme.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.786
ACE2	MEP1A	ENSOCUP00000015275	ENSOCUP00000001280	Angiotensin-converting enzyme.	Meprin A subunit.	0.920
ACE2	MEP1B	ENSOCUP00000015275	ENSOCUP00000011831	Angiotensin-converting enzyme.	Meprin A subunit.	0.904
ACE2	MME	ENSOCUP00000015275	ENSOCUP00000041310	Angiotensin-converting enzyme.	Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family.	0.973
ACE2	PHEX	ENSOCUP00000015275	ENSOCUP00000005217	Angiotensin-converting enzyme.	Phosphate regulating endopeptidase homolog X-linked.	0.425
ACE2	PRCP	ENSOCUP00000015275	ENSOCUP00000044768	Angiotensin-converting enzyme.	Prolylcarboxypeptidase.	0.933
ACE2	XPNPEP1	ENSOCUP00000015275	ENSOCUP00000030578	Angiotensin-converting enzyme.	X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.	0.644
ACE2	XPNPEP2	ENSOCUP00000015275	ENSOCUP00000022176	Angiotensin-converting enzyme.	X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.	0.884
CLTRN	GCG	ENSOCUP00000011254	ENSOCUP00000019727	Collectrin domain-containing protein.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.751
CLTRN	MEP1A	ENSOCUP00000011254	ENSOCUP00000001280	Collectrin domain-containing protein.	Meprin A subunit.	0.845
CLTRN	MEP1B	ENSOCUP00000011254	ENSOCUP00000011831	Collectrin domain-containing protein.	Meprin A subunit.	0.840
CLTRN	MME	ENSOCUP00000011254	ENSOCUP00000041310	Collectrin domain-containing protein.	Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family.	0.795
CLTRN	PHEX	ENSOCUP00000011254	ENSOCUP00000005217	Collectrin domain-containing protein.	Phosphate regulating endopeptidase homolog X-linked.	0.425
CLTRN	PRCP	ENSOCUP00000011254	ENSOCUP00000044768	Collectrin domain-containing protein.	Prolylcarboxypeptidase.	0.765
CLTRN	XPNPEP1	ENSOCUP00000011254	ENSOCUP00000030578	Collectrin domain-containing protein.	X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.	0.644
CLTRN	XPNPEP2	ENSOCUP00000011254	ENSOCUP00000022176	Collectrin domain-containing protein.	X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.	0.775
GCG	ACE2	ENSOCUP00000019727	ENSOCUP00000015275	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Angiotensin-converting enzyme.	0.786
GCG	CLTRN	ENSOCUP00000019727	ENSOCUP00000011254	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Collectrin domain-containing protein.	0.751
GCG	MEP1A	ENSOCUP00000019727	ENSOCUP00000001280	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Meprin A subunit.	0.734
GCG	MEP1B	ENSOCUP00000019727	ENSOCUP00000011831	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Meprin A subunit.	0.740