STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)    
Predicted Functional Partners:
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
   
 0.998
CIAO2A
Cytosolic iron-sulfur assembly component 2A.
    
 0.988
CIAO2B
FeS_assembly_P domain-containing protein.
    
 0.984
G1T9R6_RABIT
FeS_assembly_P domain-containing protein.
    
 0.939
ENSOCUP00000035910
FeS_assembly_P domain-containing protein.
    
 0.939
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
    
 0.912
NARF
Nuclear prelamin A recognition factor; Belongs to the NARF family.
    
 0.910
CDKAL1
CDK5 regulatory subunit associated protein 1 like 1.
    
 
 0.855
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
   
  
 0.850
POLE
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 0.805
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.