Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA4Pleckstrin homology domain containing A4. (565 aa)    
Predicted Functional Partners:
PLEKHA5
Pleckstrin homology domain containing A5.
    
0.739
TMCO3
Transmembrane and coiled-coil domains 3.
      
 0.693
KLHL12
Kelch like family member 12.
   
 0.673
ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
   
 
 0.650
PLEKHA8
Pleckstrin homology domain containing A8.
      
 0.582
G1U968_RABIT
Uncharacterized protein.
    
   0.570
DMXL1
Dmx like 1.
   
 
 0.558
PLEKHA2
Pleckstrin homology domain containing A2.
   
 0.552
PRKAA1
Non-specific serine/threonine protein kinase.
    
 
 0.520
PLEK2
Pleckstrin 2.
      
 0.517
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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