LMO2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LMO2

LIM domain only 2. (158 aa)

Predicted Functional Partners:

TAL1

0.994

LDB1

0.993

GATA1

0.981

LDB2

0.938

GATA3

0.879

TAL2

0.877

RUNX1

0.861

MYB

0.829

SSBP2

0.769

POLR2G

0.768

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA1	GATA3	ENSOCUP00000025590	ENSOCUP00000015302	GATA binding protein 1.	GATA binding protein 3.	0.617
GATA1	LDB1	ENSOCUP00000025590	ENSOCUP00000017993	GATA binding protein 1.	LIM domain binding 1.	0.898
GATA1	LDB2	ENSOCUP00000025590	ENSOCUP00000033561	GATA binding protein 1.	LIM domain binding 2.	0.729
GATA1	LMO2	ENSOCUP00000025590	ENSOCUP00000001318	GATA binding protein 1.	LIM domain only 2.	0.981
GATA1	MYB	ENSOCUP00000025590	ENSOCUP00000010004	GATA binding protein 1.	MYB proto-oncogene, transcription factor.	0.814
GATA1	RUNX1	ENSOCUP00000025590	ENSOCUP00000011814	GATA binding protein 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.912
GATA1	TAL1	ENSOCUP00000025590	ENSOCUP00000014817	GATA binding protein 1.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.989
GATA1	TAL2	ENSOCUP00000025590	ENSOCUP00000030229	GATA binding protein 1.	TAL bHLH transcription factor 2.	0.441
GATA3	GATA1	ENSOCUP00000015302	ENSOCUP00000025590	GATA binding protein 3.	GATA binding protein 1.	0.617
GATA3	LDB1	ENSOCUP00000015302	ENSOCUP00000017993	GATA binding protein 3.	LIM domain binding 1.	0.836
GATA3	LDB2	ENSOCUP00000015302	ENSOCUP00000033561	GATA binding protein 3.	LIM domain binding 2.	0.770
GATA3	LMO2	ENSOCUP00000015302	ENSOCUP00000001318	GATA binding protein 3.	LIM domain only 2.	0.879
GATA3	MYB	ENSOCUP00000015302	ENSOCUP00000010004	GATA binding protein 3.	MYB proto-oncogene, transcription factor.	0.808
GATA3	RUNX1	ENSOCUP00000015302	ENSOCUP00000011814	GATA binding protein 3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.902
GATA3	TAL1	ENSOCUP00000015302	ENSOCUP00000014817	GATA binding protein 3.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.971
GATA3	TAL2	ENSOCUP00000015302	ENSOCUP00000030229	GATA binding protein 3.	TAL bHLH transcription factor 2.	0.563
LDB1	GATA1	ENSOCUP00000017993	ENSOCUP00000025590	LIM domain binding 1.	GATA binding protein 1.	0.898
LDB1	GATA3	ENSOCUP00000017993	ENSOCUP00000015302	LIM domain binding 1.	GATA binding protein 3.	0.836
LDB1	LDB2	ENSOCUP00000017993	ENSOCUP00000033561	LIM domain binding 1.	LIM domain binding 2.	0.657
LDB1	LMO2	ENSOCUP00000017993	ENSOCUP00000001318	LIM domain binding 1.	LIM domain only 2.	0.993