TNFRSF17 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TNFRSF17

TNF receptor superfamily member 17. (183 aa)

Predicted Functional Partners:

TNLG7A

0.998

MZB1

0.988

TNFSF13

0.981

TNFRSF13B

0.808

POU2AF1

0.738

JCHAIN

0.686

MS4A1

0.623

PNOC

0.615

FCRL5

0.612

CD40LG

0.605

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40LG	MS4A1	ENSOCUP00000003395	ENSOCUP00000006862	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Membrane spanning 4-domains A1.	0.423
CD40LG	TNFRSF13B	ENSOCUP00000003395	ENSOCUP00000021430	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF receptor superfamily member 13B.	0.627
CD40LG	TNFRSF17	ENSOCUP00000003395	ENSOCUP00000001340	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF receptor superfamily member 17.	0.605
CD40LG	TNFSF13	ENSOCUP00000003395	ENSOCUP00000019439	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.417
CD40LG	TNLG7A	ENSOCUP00000003395	ENSOCUP00000010562	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor ligand 7A; Belongs to the tumor necrosis factor family.	0.923
FCRL5	JCHAIN	ENSOCUP00000007782	ENSOCUP00000023316	Fc receptor like 5.	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	0.440
FCRL5	MS4A1	ENSOCUP00000007782	ENSOCUP00000006862	Fc receptor like 5.	Membrane spanning 4-domains A1.	0.619
FCRL5	POU2AF1	ENSOCUP00000007782	ENSOCUP00000010817	Fc receptor like 5.	POU class 2 homeobox associating factor 1.	0.480
FCRL5	TNFRSF17	ENSOCUP00000007782	ENSOCUP00000001340	Fc receptor like 5.	TNF receptor superfamily member 17.	0.612
JCHAIN	FCRL5	ENSOCUP00000023316	ENSOCUP00000007782	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	Fc receptor like 5.	0.440
JCHAIN	MS4A1	ENSOCUP00000023316	ENSOCUP00000006862	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	Membrane spanning 4-domains A1.	0.511
JCHAIN	MZB1	ENSOCUP00000023316	ENSOCUP00000006001	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	Marginal zone B and B1 cell specific protein.	0.884
JCHAIN	POU2AF1	ENSOCUP00000023316	ENSOCUP00000010817	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	POU class 2 homeobox associating factor 1.	0.783
JCHAIN	TNFRSF17	ENSOCUP00000023316	ENSOCUP00000001340	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	TNF receptor superfamily member 17.	0.686
MS4A1	CD40LG	ENSOCUP00000006862	ENSOCUP00000003395	Membrane spanning 4-domains A1.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.423
MS4A1	FCRL5	ENSOCUP00000006862	ENSOCUP00000007782	Membrane spanning 4-domains A1.	Fc receptor like 5.	0.619
MS4A1	JCHAIN	ENSOCUP00000006862	ENSOCUP00000023316	Membrane spanning 4-domains A1.	Immunoglobulin J chain; Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.	0.511
MS4A1	MZB1	ENSOCUP00000006862	ENSOCUP00000006001	Membrane spanning 4-domains A1.	Marginal zone B and B1 cell specific protein.	0.799
MS4A1	PNOC	ENSOCUP00000006862	ENSOCUP00000012177	Membrane spanning 4-domains A1.	Prepronociceptin.	0.460
MS4A1	POU2AF1	ENSOCUP00000006862	ENSOCUP00000010817	Membrane spanning 4-domains A1.	POU class 2 homeobox associating factor 1.	0.736