Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LAP3Leucine aminopeptidase 3. (519 aa)    
Predicted Functional Partners:
GOT1
Aspartate aminotransferase.
   
 0.923
ANPEP
Aminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...]
   
 0.904
G1TLQ2_RABIT
Uncharacterized protein.
     
 0.890
GCLC
Glutamate-cysteine ligase catalytic subunit.
     
 0.880
GSS
Glutathione synthetase.
   
 
 0.875
P4HA3
Prolyl 4-hydroxylase subunit alpha 3.
     
 0.874
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
   
 
 0.873
GGT7
Gamma-glutamyltransferase 7.
     
 0.870
GGT5
Gamma-glutamyltransferase 5.
     
 0.870
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
     
 0.870
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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