Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMDEC1ADAM like decysin 1. (495 aa)    
Predicted Functional Partners:
HCST
Hematopoietic cell signal transducer.
      
 0.549
DPEP1
Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
   
  
 0.528
OR5R1
Olfactory receptor.
      
 0.510
PNMA8A
PNMA family member 8A.
      
 0.483
ZYG11A
Zyg-11 family member A, cell cycle regulator.
      
 0.479
OR51A7
Olfactory receptor family 51 subfamily A member 7.
      
 0.479
ADAMTSL4
ADAMTS like 4.
      
 0.472
CHIT1
Chitinase 1; Belongs to the glycosyl hydrolase 18 family.
     
 0.430
MMP12
Macrophage metalloelastase; May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). Belongs to the peptidase M10A family.
   
  
 0.426
CALHM4
Uncharacterized protein.
      
 0.419
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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