Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G1SFT5_RABITUncharacterized protein. (515 aa)    
Predicted Functional Partners:
CHD1L
Chromodomain helicase DNA binding protein 1 like.
 
 
 
 0.906
CHD2
DUF4208 domain-containing protein.
 
      0.900
ENSOCUP00000045944
Helicase C-terminal domain-containing protein.
 
      0.899
SSRP1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
    
 
 0.581
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.562
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.537
SUPT16H
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.517
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 
 0.511
RAD54L
RAD54 like.
 
    
 0.508
ARID4B
AT-rich interaction domain 4B.
   
 0.502
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (60%) [HD]