HPS1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

HPS1

HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (703 aa)

Predicted Functional Partners:

HPS4

0.834

HPD

0.621

HPDL

0.617

HPS3

0.584

BLOC1S6

0.526

BLOC1S1

0.492

HPS5

0.458

RAB29

0.449

RAB38

0.447

RAB32

0.447

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLOC1S1	BLOC1S6	ENSOCUP00000039473	ENSOCUP00000014909	Uncharacterized protein.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.946
BLOC1S1	HPS1	ENSOCUP00000039473	ENSOCUP00000001401	Uncharacterized protein.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.492
BLOC1S1	HPS4	ENSOCUP00000039473	ENSOCUP00000005435	Uncharacterized protein.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.409
BLOC1S1	HPS5	ENSOCUP00000039473	ENSOCUP00000046179	Uncharacterized protein.	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.515
BLOC1S6	BLOC1S1	ENSOCUP00000014909	ENSOCUP00000039473	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	Uncharacterized protein.	0.946
BLOC1S6	HPS1	ENSOCUP00000014909	ENSOCUP00000001401	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.526
BLOC1S6	HPS3	ENSOCUP00000014909	ENSOCUP00000048559	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	0.842
BLOC1S6	HPS4	ENSOCUP00000014909	ENSOCUP00000005435	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.440
BLOC1S6	HPS5	ENSOCUP00000014909	ENSOCUP00000046179	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.917
HPD	HPS1	ENSOCUP00000010159	ENSOCUP00000001401	4-hydroxyphenylpyruvate dioxygenase.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.621
HPDL	HPS1	ENSOCUP00000001690	ENSOCUP00000001401	4-hydroxyphenylpyruvate dioxygenase.	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	0.617
HPS1	BLOC1S1	ENSOCUP00000001401	ENSOCUP00000039473	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	Uncharacterized protein.	0.492
HPS1	BLOC1S6	ENSOCUP00000001401	ENSOCUP00000014909	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.526
HPS1	HPD	ENSOCUP00000001401	ENSOCUP00000010159	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	4-hydroxyphenylpyruvate dioxygenase.	0.621
HPS1	HPDL	ENSOCUP00000001401	ENSOCUP00000001690	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	4-hydroxyphenylpyruvate dioxygenase.	0.617
HPS1	HPS3	ENSOCUP00000001401	ENSOCUP00000048559	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	Hermansky-Pudlak syndrome 3 protein homolog; Involved in early stages of melanosome biogenesis and maturation.	0.584
HPS1	HPS4	ENSOCUP00000001401	ENSOCUP00000005435	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.	0.834
HPS1	HPS5	ENSOCUP00000001401	ENSOCUP00000046179	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.	0.458
HPS1	RAB29	ENSOCUP00000001401	ENSOCUP00000032172	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	RAB29, member RAS oncogene family.	0.449
HPS1	RAB32	ENSOCUP00000001401	ENSOCUP00000022083	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1.	Uncharacterized protein.	0.447