HPSE2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HPSE2

Heparanase 2 (inactive). (592 aa)

Predicted Functional Partners:

SDC1

0.768

WFDC5

0.628

PSD3

0.526

CHD1L

0.524

LRIG2

0.497

GPC3

0.492

MRVI1

0.476

SDC3

0.473

KLHL1

0.466

CFAP45

0.466

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP45	HPSE2	ENSOCUP00000035767	ENSOCUP00000001405	Cilia and flagella associated protein 45.	Heparanase 2 (inactive).	0.466
CHD1L	HPSE2	ENSOCUP00000008061	ENSOCUP00000001405	Chromodomain helicase DNA binding protein 1 like.	Heparanase 2 (inactive).	0.524
GPC3	HPSE2	ENSOCUP00000001504	ENSOCUP00000001405	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Heparanase 2 (inactive).	0.492
GPC3	SDC1	ENSOCUP00000001504	ENSOCUP00000020777	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.792
GPC3	SDC3	ENSOCUP00000001504	ENSOCUP00000005912	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.785
HPSE2	CFAP45	ENSOCUP00000001405	ENSOCUP00000035767	Heparanase 2 (inactive).	Cilia and flagella associated protein 45.	0.466
HPSE2	CHD1L	ENSOCUP00000001405	ENSOCUP00000008061	Heparanase 2 (inactive).	Chromodomain helicase DNA binding protein 1 like.	0.524
HPSE2	GPC3	ENSOCUP00000001405	ENSOCUP00000001504	Heparanase 2 (inactive).	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.492
HPSE2	KLHL1	ENSOCUP00000001405	ENSOCUP00000013034	Heparanase 2 (inactive).	Kelch like family member 1.	0.466
HPSE2	LRIG2	ENSOCUP00000001405	ENSOCUP00000008845	Heparanase 2 (inactive).	Leucine rich repeats and immunoglobulin like domains 2.	0.497
HPSE2	MRVI1	ENSOCUP00000001405	ENSOCUP00000039261	Heparanase 2 (inactive).	Murine retrovirus integration site 1 homolog.	0.476
HPSE2	PSD3	ENSOCUP00000001405	ENSOCUP00000018083	Heparanase 2 (inactive).	Pleckstrin and Sec7 domain containing 3.	0.526
HPSE2	SDC1	ENSOCUP00000001405	ENSOCUP00000020777	Heparanase 2 (inactive).	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.768
HPSE2	SDC3	ENSOCUP00000001405	ENSOCUP00000005912	Heparanase 2 (inactive).	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.473
HPSE2	WFDC5	ENSOCUP00000001405	ENSOCUP00000017797	Heparanase 2 (inactive).	WAP four-disulfide core domain 5.	0.628
KLHL1	HPSE2	ENSOCUP00000013034	ENSOCUP00000001405	Kelch like family member 1.	Heparanase 2 (inactive).	0.466
LRIG2	HPSE2	ENSOCUP00000008845	ENSOCUP00000001405	Leucine rich repeats and immunoglobulin like domains 2.	Heparanase 2 (inactive).	0.497
MRVI1	HPSE2	ENSOCUP00000039261	ENSOCUP00000001405	Murine retrovirus integration site 1 homolog.	Heparanase 2 (inactive).	0.476
PSD3	HPSE2	ENSOCUP00000018083	ENSOCUP00000001405	Pleckstrin and Sec7 domain containing 3.	Heparanase 2 (inactive).	0.526
SDC1	GPC3	ENSOCUP00000020777	ENSOCUP00000001504	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.792