STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LNPEPLeucyl and cystinyl aminopeptidase. (1025 aa)    
Predicted Functional Partners:
TBC1D4
TBC1 domain family member 4.
   
 
 0.753
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.671
C5orf30
Chromosome 5 open reading frame 30.
      
 0.649
LAP3
Leucine aminopeptidase 3.
   
 
 0.639
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
   
 
 0.627
CD4
T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
      
 0.625
SERINC1
Serine incorporator 1.
      
 0.586
TNKS2
Poly [ADP-ribose] polymerase.
   
 
 0.584
DAGLB
Diacylglycerol lipase beta.
      
 0.580
SAMD4A
Sterile alpha motif domain containing 4A.
   
 
 0.565
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.