Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.999
PLK1
Serine/threonine-protein kinase PLK.
   
 0.996
CDC20B
Cell division cycle 20B.
   
 0.989
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.979
PTTG1
Uncharacterized protein.
   
 
 0.978
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.973
BIRC5
Uncharacterized protein.
   
 0.964
FOXM1
Forkhead box M1.
   
 0.962
CDC27
Cell division cycle 27.
   
 0.961
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.959
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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