STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA4Protein disulfide-isomerase. (646 aa)    
Predicted Functional Partners:
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.991
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
0.988
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.985
HSP90B1
Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
   
 0.982
HYOU1
Hypoxia up-regulated 1.
   
 0.976
TXNDC5
Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family.
   
0.968
CALR3
Calreticulin.
   
 0.964
CALR
Calreticulin.
   
 0.959
ERP29
Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase.
   
 0.950
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.891
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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