PHF21A protein (Oryctolagus cuniculus) - STRING interaction network

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Score

PHF21A

PHD finger protein 21A. (681 aa)

Predicted Functional Partners:

KDM1A

0.996

RCOR1

0.996

HMG20A

0.974

HDAC2

0.933

RCOR2

0.906

HDAC1

0.894

RCOR3

0.890

ENSOCUP00000034777

0.874

HDAC8

0.714

LOC100348409

0.703

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000034777	HDAC2	ENSOCUP00000034777	ENSOCUP00000040151	Uncharacterized protein.	Histone deacetylase 2.	0.991
ENSOCUP00000034777	HDAC8	ENSOCUP00000034777	ENSOCUP00000027639	Uncharacterized protein.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.472
ENSOCUP00000034777	HMG20A	ENSOCUP00000034777	ENSOCUP00000004899	Uncharacterized protein.	High mobility group 20A.	0.808
ENSOCUP00000034777	KDM1A	ENSOCUP00000034777	ENSOCUP00000001013	Uncharacterized protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.911
ENSOCUP00000034777	PHF21A	ENSOCUP00000034777	ENSOCUP00000001434	Uncharacterized protein.	PHD finger protein 21A.	0.874
ENSOCUP00000034777	RCOR1	ENSOCUP00000034777	ENSOCUP00000043168	Uncharacterized protein.	REST corepressor 1.	0.965
ENSOCUP00000034777	RCOR2	ENSOCUP00000034777	ENSOCUP00000025542	Uncharacterized protein.	REST corepressor 2.	0.731
ENSOCUP00000034777	RCOR3	ENSOCUP00000034777	ENSOCUP00000007879	Uncharacterized protein.	REST corepressor 3.	0.859
HDAC1	HDAC2	ENSOCUP00000037903	ENSOCUP00000040151	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.998
HDAC1	HDAC8	ENSOCUP00000037903	ENSOCUP00000027639	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.548
HDAC1	HMG20A	ENSOCUP00000037903	ENSOCUP00000004899	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	High mobility group 20A.	0.840
HDAC1	KDM1A	ENSOCUP00000037903	ENSOCUP00000001013	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.953
HDAC1	PHF21A	ENSOCUP00000037903	ENSOCUP00000001434	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	PHD finger protein 21A.	0.894
HDAC1	RCOR1	ENSOCUP00000037903	ENSOCUP00000043168	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 1.	0.972
HDAC1	RCOR2	ENSOCUP00000037903	ENSOCUP00000025542	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 2.	0.794
HDAC1	RCOR3	ENSOCUP00000037903	ENSOCUP00000007879	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 3.	0.914
HDAC2	ENSOCUP00000034777	ENSOCUP00000040151	ENSOCUP00000034777	Histone deacetylase 2.	Uncharacterized protein.	0.991
HDAC2	HDAC1	ENSOCUP00000040151	ENSOCUP00000037903	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.998
HDAC2	HDAC8	ENSOCUP00000040151	ENSOCUP00000027639	Histone deacetylase 2.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.558
HDAC2	HMG20A	ENSOCUP00000040151	ENSOCUP00000004899	Histone deacetylase 2.	High mobility group 20A.	0.948