SDHAF2 protein (Oryctolagus cuniculus) - STRING interaction network

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SDHAF2

Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)

Predicted Functional Partners:

SDHA

0.978

SDHB

0.900

SDHC

0.884

TMEM127

0.770

SDHAF1

0.739

TEX49

0.641

CCDC105

0.640

TEKT2

0.638

CFAP52

0.631

MDH2

0.623

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC105	CFAP52	ENSOCUP00000025008	ENSOCUP00000013289	Coiled-coil domain containing 105.	Cilia and flagella associated protein 52.	0.872
CCDC105	SDHAF2	ENSOCUP00000025008	ENSOCUP00000001442	Coiled-coil domain containing 105.	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.	0.640
CCDC105	TEKT2	ENSOCUP00000025008	ENSOCUP00000009487	Coiled-coil domain containing 105.	Tektin 2.	0.871
CCDC105	TEX49	ENSOCUP00000025008	ENSOCUP00000006387	Coiled-coil domain containing 105.	Testis expressed 49.	0.803
CFAP52	CCDC105	ENSOCUP00000013289	ENSOCUP00000025008	Cilia and flagella associated protein 52.	Coiled-coil domain containing 105.	0.872
CFAP52	SDHAF2	ENSOCUP00000013289	ENSOCUP00000001442	Cilia and flagella associated protein 52.	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.	0.631
CFAP52	TEKT2	ENSOCUP00000013289	ENSOCUP00000009487	Cilia and flagella associated protein 52.	Tektin 2.	0.883
CFAP52	TEX49	ENSOCUP00000013289	ENSOCUP00000006387	Cilia and flagella associated protein 52.	Testis expressed 49.	0.782
MDH2	SDHA	ENSOCUP00000035179	ENSOCUP00000025370	Malate dehydrogenase 2.	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.966
MDH2	SDHAF1	ENSOCUP00000035179	ENSOCUP00000011985	Malate dehydrogenase 2.	Succinate dehydrogenase complex assembly factor 1; Belongs to the complex I LYR family.	0.437
MDH2	SDHAF2	ENSOCUP00000035179	ENSOCUP00000001442	Malate dehydrogenase 2.	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.	0.623
MDH2	SDHB	ENSOCUP00000035179	ENSOCUP00000031100	Malate dehydrogenase 2.	Succinate dehydrogenase complex iron sulfur subunit B.	0.980
MDH2	SDHC	ENSOCUP00000035179	ENSOCUP00000049628	Malate dehydrogenase 2.	Succinate dehydrogenase complex subunit C.	0.778
MDH2	TMEM127	ENSOCUP00000035179	ENSOCUP00000008490	Malate dehydrogenase 2.	Transmembrane protein 127.	0.584
SDHA	MDH2	ENSOCUP00000025370	ENSOCUP00000035179	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Malate dehydrogenase 2.	0.966
SDHA	SDHAF1	ENSOCUP00000025370	ENSOCUP00000011985	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Succinate dehydrogenase complex assembly factor 1; Belongs to the complex I LYR family.	0.971
SDHA	SDHAF2	ENSOCUP00000025370	ENSOCUP00000001442	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.	0.978
SDHA	SDHB	ENSOCUP00000025370	ENSOCUP00000031100	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Succinate dehydrogenase complex iron sulfur subunit B.	0.999
SDHA	SDHC	ENSOCUP00000025370	ENSOCUP00000049628	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Succinate dehydrogenase complex subunit C.	0.999
SDHA	TMEM127	ENSOCUP00000025370	ENSOCUP00000008490	Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	Transmembrane protein 127.	0.733

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