Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C14orf119Chromosome 14 open reading frame 119. (142 aa)    
Predicted Functional Partners:
SEL1L2
SEL1L2 adaptor subunit of ERAD E3 ligase.
   
 
 0.762
HEATR3
HEAT repeat containing 3.
   
  
 0.744
AK9
Uncharacterized protein.
    
 0.722
ZNF397
Zinc finger protein 397.
    
 0.683
C11orf74
Chromosome 11 open reading frame 74.
      
 0.673
EFCAB7
EF-hand calcium binding domain 7.
    
 0.670
PYROXD1
Pyridine nucleotide-disulphide oxidoreductase domain 1.
    
 
 0.644
STN1
CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
   
 
 0.638
OR2L13
Olfactory receptor.
     
 0.602
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.602
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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