STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPRMReprimo, TP53 dependent G2 arrest mediator homolog. (109 aa)    
Predicted Functional Partners:
CPLX3
Complexin 3.
      
 0.553
CARNMT1
Carnosine N-methyltransferase 1.
      
 0.541
PTCHD4
Patched domain containing 4.
      
 0.527
INSM2
INSM transcriptional repressor 2.
   
  
 0.516
GML
Glycosylphosphatidylinositol anchored molecule like.
      
 0.502
MDM4
Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.
      
 0.461
MPPED2
Metallophosphoesterase domain containing 2.
   
  
 0.458
PKDCC
Protein kinase domain containing, cytoplasmic.
      
 0.447
EDN2
Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family.
  
     0.440
FRMD8
FERM domain containing 8.
      
 0.430
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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