Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXF1Forkhead box F1. (433 aa)    
Predicted Functional Partners:
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.788
BMP4
Bone morphogenetic protein 4; Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).
     
 0.774
GATA4
GATA binding protein 4.
   
 0.749
PAX1
Paired box 1.
   
  
 0.713
CA12
Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.
      
 0.672
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.628
FOXF2
Forkhead box F2.
  
 
0.618
HOXB6
Homeobox B6.
   
 0.616
BARX1
BARX homeobox 1.
    
 0.602
TBX6
T-box transcription factor 6.
     
 0.601
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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