LRRC8A protein (Oryctolagus cuniculus) - STRING interaction network

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Score

LRRC8A

Leucine rich repeat containing 8 VRAC subunit A. (769 aa)

Predicted Functional Partners:

LRRC8B

0.985

LRRC8E

0.981

LRRC8C

0.975

LRRC8D

0.971

NPEPPS

0.747

TTYH2

0.625

LRRC10

0.619

CLCN3

0.596

BEST2

0.581

TTYH3

0.578

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEST2	CLCN3	ENSOCUP00000017513	ENSOCUP00000029152	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	0.648
BEST2	LRRC8A	ENSOCUP00000017513	ENSOCUP00000001484	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Leucine rich repeat containing 8 VRAC subunit A.	0.581
BEST2	LRRC8B	ENSOCUP00000017513	ENSOCUP00000009276	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Leucine rich repeat containing 8 VRAC subunit B.	0.581
BEST2	LRRC8D	ENSOCUP00000017513	ENSOCUP00000025921	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Leucine rich repeat containing 8 VRAC subunit D.	0.483
CLCN3	BEST2	ENSOCUP00000029152	ENSOCUP00000017513	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	0.648
CLCN3	LRRC8A	ENSOCUP00000029152	ENSOCUP00000001484	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	Leucine rich repeat containing 8 VRAC subunit A.	0.596
CLCN3	LRRC8B	ENSOCUP00000029152	ENSOCUP00000009276	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	Leucine rich repeat containing 8 VRAC subunit B.	0.502
CLCN3	LRRC8C	ENSOCUP00000029152	ENSOCUP00000009277	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	Leucine rich repeat containing 8 VRAC subunit C.	0.479
CLCN3	LRRC8D	ENSOCUP00000029152	ENSOCUP00000025921	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	Leucine rich repeat containing 8 VRAC subunit D.	0.591
CLCN3	LRRC8E	ENSOCUP00000029152	ENSOCUP00000025873	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	Leucine rich repeat containing 8 VRAC subunit E.	0.452
LRRC10	LRRC8A	ENSOCUP00000014788	ENSOCUP00000001484	Uncharacterized protein.	Leucine rich repeat containing 8 VRAC subunit A.	0.619
LRRC10	LRRC8B	ENSOCUP00000014788	ENSOCUP00000009276	Uncharacterized protein.	Leucine rich repeat containing 8 VRAC subunit B.	0.492
LRRC8A	BEST2	ENSOCUP00000001484	ENSOCUP00000017513	Leucine rich repeat containing 8 VRAC subunit A.	Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	0.581
LRRC8A	CLCN3	ENSOCUP00000001484	ENSOCUP00000029152	Leucine rich repeat containing 8 VRAC subunit A.	H(+)/Cl(-) exchange transporter 3; Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory (By similarity); Belongs to the chloride channel (TC 2.A.49) family. ClC- 3/CLCN3 subfamily.	0.596
LRRC8A	LRRC10	ENSOCUP00000001484	ENSOCUP00000014788	Leucine rich repeat containing 8 VRAC subunit A.	Uncharacterized protein.	0.619
LRRC8A	LRRC8B	ENSOCUP00000001484	ENSOCUP00000009276	Leucine rich repeat containing 8 VRAC subunit A.	Leucine rich repeat containing 8 VRAC subunit B.	0.985
LRRC8A	LRRC8C	ENSOCUP00000001484	ENSOCUP00000009277	Leucine rich repeat containing 8 VRAC subunit A.	Leucine rich repeat containing 8 VRAC subunit C.	0.975
LRRC8A	LRRC8D	ENSOCUP00000001484	ENSOCUP00000025921	Leucine rich repeat containing 8 VRAC subunit A.	Leucine rich repeat containing 8 VRAC subunit D.	0.971
LRRC8A	LRRC8E	ENSOCUP00000001484	ENSOCUP00000025873	Leucine rich repeat containing 8 VRAC subunit A.	Leucine rich repeat containing 8 VRAC subunit E.	0.981
LRRC8A	NPEPPS	ENSOCUP00000001484	ENSOCUP00000023664	Leucine rich repeat containing 8 VRAC subunit A.	Aminopeptidase.	0.747