G1SG29_RABIT protein (Oryctolagus cuniculus)

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Score

G1SG29_RABIT

Skp1_POZ domain-containing protein. (72 aa)

Predicted Functional Partners:

CUL5

0.941

CUL2

0.941

UBXN7

0.937

HIF1A

0.931

VHL

0.928

ELOB

0.891

G1U1I7_RABIT

0.891

SOCS4

0.863

EPAS1

0.859

SOCS2

0.855

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL2	CUL5	ENSOCUP00000012675	ENSOCUP00000009389	Cullin 2; Belongs to the cullin family.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.807
CUL2	ELOB	ENSOCUP00000012675	ENSOCUP00000008716	Cullin 2; Belongs to the cullin family.	Elongin B.	0.996
CUL2	EPAS1	ENSOCUP00000012675	ENSOCUP00000021497	Cullin 2; Belongs to the cullin family.	Endothelial PAS domain protein 1.	0.955
CUL2	G1SG29_RABIT	ENSOCUP00000012675	ENSOCUP00000001516	Cullin 2; Belongs to the cullin family.	Skp1_POZ domain-containing protein.	0.941
CUL2	G1U1I7_RABIT	ENSOCUP00000012675	ENSOCUP00000023222	Cullin 2; Belongs to the cullin family.	Uncharacterized protein.	0.964
CUL2	HIF1A	ENSOCUP00000012675	ENSOCUP00000041090	Cullin 2; Belongs to the cullin family.	Uncharacterized protein.	0.992
CUL2	SOCS2	ENSOCUP00000012675	ENSOCUP00000001084	Cullin 2; Belongs to the cullin family.	Suppressor of cytokine signaling 2.	0.475
CUL2	SOCS4	ENSOCUP00000012675	ENSOCUP00000003465	Cullin 2; Belongs to the cullin family.	Suppressor of cytokine signaling 4.	0.623
CUL2	UBXN7	ENSOCUP00000012675	ENSOCUP00000010586	Cullin 2; Belongs to the cullin family.	UBX domain-containing protein.	0.986
CUL2	VHL	ENSOCUP00000012675	ENSOCUP00000027793	Cullin 2; Belongs to the cullin family.	Uncharacterized protein.	0.991
CUL5	CUL2	ENSOCUP00000009389	ENSOCUP00000012675	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Cullin 2; Belongs to the cullin family.	0.807
CUL5	ELOB	ENSOCUP00000009389	ENSOCUP00000008716	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Elongin B.	0.996
CUL5	G1SG29_RABIT	ENSOCUP00000009389	ENSOCUP00000001516	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Skp1_POZ domain-containing protein.	0.941
CUL5	G1U1I7_RABIT	ENSOCUP00000009389	ENSOCUP00000023222	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Uncharacterized protein.	0.964
CUL5	SOCS2	ENSOCUP00000009389	ENSOCUP00000001084	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Suppressor of cytokine signaling 2.	0.984
CUL5	SOCS4	ENSOCUP00000009389	ENSOCUP00000003465	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Suppressor of cytokine signaling 4.	0.982
CUL5	VHL	ENSOCUP00000009389	ENSOCUP00000027793	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	Uncharacterized protein.	0.460
ELOB	CUL2	ENSOCUP00000008716	ENSOCUP00000012675	Elongin B.	Cullin 2; Belongs to the cullin family.	0.996
ELOB	CUL5	ENSOCUP00000008716	ENSOCUP00000009389	Elongin B.	Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...]	0.996
ELOB	EPAS1	ENSOCUP00000008716	ENSOCUP00000021497	Elongin B.	Endothelial PAS domain protein 1.	0.917