REST protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

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Score

REST

RE1 silencing transcription factor. (930 aa)

Predicted Functional Partners:

RCOR1

0.995

HDAC1

0.970

HTT

0.960

SIN3A

0.954

KDM1A

0.899

RCOR2

0.883

RCOR3

0.790

G1TZ09_RABIT

0.751

ENSOCUP00000045227

0.751

HDAC2

0.703

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000045227	HDAC1	ENSOCUP00000045227	ENSOCUP00000037903	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.806
ENSOCUP00000045227	HDAC2	ENSOCUP00000045227	ENSOCUP00000040151	Uncharacterized protein.	Histone deacetylase 2.	0.829
ENSOCUP00000045227	REST	ENSOCUP00000045227	ENSOCUP00000001526	Uncharacterized protein.	RE1 silencing transcription factor.	0.751
ENSOCUP00000045227	SIN3A	ENSOCUP00000045227	ENSOCUP00000034155	Uncharacterized protein.	SIN3 transcription regulator family member A.	0.738
G1TZ09_RABIT	HDAC1	ENSOCUP00000022327	ENSOCUP00000037903	Sin3a_C domain-containing protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.806
G1TZ09_RABIT	HDAC2	ENSOCUP00000022327	ENSOCUP00000040151	Sin3a_C domain-containing protein.	Histone deacetylase 2.	0.829
G1TZ09_RABIT	REST	ENSOCUP00000022327	ENSOCUP00000001526	Sin3a_C domain-containing protein.	RE1 silencing transcription factor.	0.751
G1TZ09_RABIT	SIN3A	ENSOCUP00000022327	ENSOCUP00000034155	Sin3a_C domain-containing protein.	SIN3 transcription regulator family member A.	0.725
HDAC1	ENSOCUP00000045227	ENSOCUP00000037903	ENSOCUP00000045227	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Uncharacterized protein.	0.806
HDAC1	G1TZ09_RABIT	ENSOCUP00000037903	ENSOCUP00000022327	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Sin3a_C domain-containing protein.	0.806
HDAC1	HDAC2	ENSOCUP00000037903	ENSOCUP00000040151	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.998
HDAC1	KDM1A	ENSOCUP00000037903	ENSOCUP00000001013	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.988
HDAC1	RCOR1	ENSOCUP00000037903	ENSOCUP00000043168	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 1.	0.987
HDAC1	RCOR2	ENSOCUP00000037903	ENSOCUP00000025542	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 2.	0.791
HDAC1	RCOR3	ENSOCUP00000037903	ENSOCUP00000007879	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	REST corepressor 3.	0.827
HDAC1	REST	ENSOCUP00000037903	ENSOCUP00000001526	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	RE1 silencing transcription factor.	0.970
HDAC1	SIN3A	ENSOCUP00000037903	ENSOCUP00000034155	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	SIN3 transcription regulator family member A.	0.999
HDAC2	ENSOCUP00000045227	ENSOCUP00000040151	ENSOCUP00000045227	Histone deacetylase 2.	Uncharacterized protein.	0.829
HDAC2	G1TZ09_RABIT	ENSOCUP00000040151	ENSOCUP00000022327	Histone deacetylase 2.	Sin3a_C domain-containing protein.	0.829
HDAC2	HDAC1	ENSOCUP00000040151	ENSOCUP00000037903	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.998