PREX2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

PREX2

Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1606 aa)

Predicted Functional Partners:

GNB5

0.840

GNB3

0.840

RAC1

0.828

RAC2

0.828

GNG4

0.826

PIK3CA

0.803

ENSOCUP00000027633

0.792

PIK3CD

0.791

PIK3CB

0.779

GNG5

0.775

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000027633	GNB3	ENSOCUP00000027633	ENSOCUP00000011129	Uncharacterized protein.	G protein subunit beta 3.	0.743
ENSOCUP00000027633	GNB5	ENSOCUP00000027633	ENSOCUP00000010220	Uncharacterized protein.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.776
ENSOCUP00000027633	GNG4	ENSOCUP00000027633	ENSOCUP00000005907	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.543
ENSOCUP00000027633	GNG5	ENSOCUP00000027633	ENSOCUP00000035600	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.745
ENSOCUP00000027633	PIK3CA	ENSOCUP00000027633	ENSOCUP00000026298	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.802
ENSOCUP00000027633	PIK3CB	ENSOCUP00000027633	ENSOCUP00000004241	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.872
ENSOCUP00000027633	PIK3CD	ENSOCUP00000027633	ENSOCUP00000021004	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.800
ENSOCUP00000027633	PREX2	ENSOCUP00000027633	ENSOCUP00000001534	Uncharacterized protein.	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.	0.792
GNB3	ENSOCUP00000027633	ENSOCUP00000011129	ENSOCUP00000027633	G protein subunit beta 3.	Uncharacterized protein.	0.743
GNB3	GNB5	ENSOCUP00000011129	ENSOCUP00000010220	G protein subunit beta 3.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.874
GNB3	GNG4	ENSOCUP00000011129	ENSOCUP00000005907	G protein subunit beta 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.995
GNB3	GNG5	ENSOCUP00000011129	ENSOCUP00000035600	G protein subunit beta 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.987
GNB3	PIK3CA	ENSOCUP00000011129	ENSOCUP00000026298	G protein subunit beta 3.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.876
GNB3	PIK3CB	ENSOCUP00000011129	ENSOCUP00000004241	G protein subunit beta 3.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.866
GNB3	PIK3CD	ENSOCUP00000011129	ENSOCUP00000021004	G protein subunit beta 3.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.866
GNB3	PREX2	ENSOCUP00000011129	ENSOCUP00000001534	G protein subunit beta 3.	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.	0.840
GNB3	RAC1	ENSOCUP00000011129	ENSOCUP00000008574	G protein subunit beta 3.	Rac family small GTPase 1.	0.805
GNB3	RAC2	ENSOCUP00000011129	ENSOCUP00000033582	G protein subunit beta 3.	Rac family small GTPase 2.	0.805
GNB5	ENSOCUP00000027633	ENSOCUP00000010220	ENSOCUP00000027633	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Uncharacterized protein.	0.776
GNB5	GNB3	ENSOCUP00000010220	ENSOCUP00000011129	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	G protein subunit beta 3.	0.874