Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACAP2Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). (785 aa)    
Predicted Functional Partners:
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
   
 0.839
RAB35
Uncharacterized protein.
   
 
 0.830
RUSC2
RUN and SH3 domain containing 2.
      
 0.770
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 
 0.750
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
0.734
DENND6B
DENN domain containing 6B.
      
 0.728
MICAL1
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
   
  
 0.677
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 0.674
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
    
 0.639
GIT2
GIT ArfGAP 2.
   
 
0.625
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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