STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACAP2Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6). (785 aa)    
Predicted Functional Partners:
RAB35
Uncharacterized protein.
   
 
 0.993
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
   
 0.869
OCRL
OCRL inositol polyphosphate-5-phosphatase.
    
 
 0.779
DENND6B
DENN domain containing 6B.
      
 0.763
RUSC2
RUN and SH3 domain containing 2.
      
 0.733
MICAL1
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
   
  
 0.699
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
   
 
0.691
DENND1A
DENN domain containing 1A.
   
  
 0.642
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
0.641
TBC1D10A
Rab-GAP TBC domain-containing protein.
   
  
 0.621
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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