| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABCE1 | EIF2S3 | ENSOCUP00000001567 | ENSOCUP00000028398 | Uncharacterized protein. | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | 0.929 |
| ABCE1 | EIF3J | ENSOCUP00000001567 | ENSOCUP00000004662 | Uncharacterized protein. | Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.959 |
| ABCE1 | ETF1 | ENSOCUP00000001567 | ENSOCUP00000005745 | Uncharacterized protein. | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | 0.994 |
| ABCE1 | RPS10 | ENSOCUP00000001567 | ENSOCUP00000044899 | Uncharacterized protein. | S10_plectin domain-containing protein. | 0.925 |
| ABCE1 | RPS12 | ENSOCUP00000001567 | ENSOCUP00000001378 | Uncharacterized protein. | 40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. | 0.927 |
| ABCE1 | RPS15 | ENSOCUP00000001567 | ENSOCUP00000022933 | Uncharacterized protein. | Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. | 0.952 |
| ABCE1 | RPS25 | ENSOCUP00000001567 | ENSOCUP00000014824 | Uncharacterized protein. | 40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. | 0.931 |
| ABCE1 | RPS28 | ENSOCUP00000001567 | ENSOCUP00000016683 | Uncharacterized protein. | Ribosomal protein S28. | 0.942 |
| ABCE1 | RPS3 | ENSOCUP00000001567 | ENSOCUP00000018598 | Uncharacterized protein. | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. | 0.946 |
| ABCE1 | RPS5 | ENSOCUP00000001567 | ENSOCUP00000026493 | Uncharacterized protein. | Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. | 0.953 |
| EIF2S3 | ABCE1 | ENSOCUP00000028398 | ENSOCUP00000001567 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Uncharacterized protein. | 0.929 |
| EIF2S3 | EIF3J | ENSOCUP00000028398 | ENSOCUP00000004662 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.950 |
| EIF2S3 | ETF1 | ENSOCUP00000028398 | ENSOCUP00000005745 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes. | 0.836 |
| EIF2S3 | RPS10 | ENSOCUP00000028398 | ENSOCUP00000044899 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | S10_plectin domain-containing protein. | 0.805 |
| EIF2S3 | RPS12 | ENSOCUP00000028398 | ENSOCUP00000001378 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | 40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. | 0.877 |
| EIF2S3 | RPS15 | ENSOCUP00000028398 | ENSOCUP00000022933 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. | 0.912 |
| EIF2S3 | RPS25 | ENSOCUP00000028398 | ENSOCUP00000014824 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | 40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. | 0.854 |
| EIF2S3 | RPS28 | ENSOCUP00000028398 | ENSOCUP00000016683 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Ribosomal protein S28. | 0.953 |
| EIF2S3 | RPS3 | ENSOCUP00000028398 | ENSOCUP00000018598 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. | 0.938 |
| EIF2S3 | RPS5 | ENSOCUP00000028398 | ENSOCUP00000026493 | Eukaryotic translation initiation factor 2 subunit 3; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyz [...] | Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. | 0.929 |
