Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (346 aa)    
Predicted Functional Partners:
AQP7
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.974
AQP10
Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
 0.969
AQP11
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
   
 
 0.938
GHRHR
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.743
AQP4
Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.729
AQP6
Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.719
AQP2
Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.708
AQP9
Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.682
AQP3
Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.679
LCMT1
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
 
 
  
 0.656
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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